Chemotherapy - Chemotherapy medicines can be given orally or through an injection into a vein. Some chemotherapy drugs for SLL are: Cytoxan or Neosar (cyclophosphamide), Fludara (fludarabine), Leukeran (chlorambucil), Nipent (pentostatin), Treanda or Bendeka (bendamustine), and Revlimid (lenalidomide). These drugs are often used in combination with each other or with another type of medicine.
Monoclonal Antibodies - These medicines use the body’s natural immune system to fight cancer. They’re typically administered by an injection and are often given along with chemotherapy or another type of drug. Monoclonal antibodies that are used for SLL may include: Rituxan (rituximab), Campath (alemtuzumab), Gazyva (obinutuzumab), and Arzerra (ofatumumab).
Targeted Treatments - These therapies attack different targets on cancer cells. Imbruvica (Ibrutinib) and Zydelig (idelalisib) are examples of targeted treatments for SLL. Both of these medicines are pills that are taken by mouth and are sometimes used with other therapies.
Steroids Steroids - may be used to destroy cancer cells or treat autoimmune issues in people with SLL or CLL.
Radiation Radiation - therapy uses high energy rays to destroy cancer cells. It’s occasionally used in people with SLL.
Bone Marrow Transplant - A bone marrow transplant, also called a “stem cell transplant,” may be an option for some people with SLL. It involves collecting stem cells from the blood or bone marrow of the patient or a matched donor. These cells are given back to the patient to restore damaged bone marrow after they receive high doses of chemotherapy, which wipe out the remaining bone marrow in their body. Because it can be hard on your body, a bone marrow transplant is often only performed on healthy, younger people.
Splenectomy Surgery - to remove the spleen doesn’t treat SLL itself, but some people might need to have it if they develop complications.
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